WebI graduated of State Engineering University of Armenia and got my bachelor’s and master’s degrees in the years of 1999 and 2001 respectively. I received my PhD in Moscow from VNIIAES (All Russian Research Institute for NPP Operation) in 2005. I started working at the Armenian Nuclear Power Plant (ANPP) at the Department of Nuclear Safety and … WebDec 20, 2007 · For some time synovial fibroblasts have been regarded simply as innocent synovial cells, mainly responsible for synovial homeostasis. During the past decade, however, a body of evidence has accumulated illustrating that rheumatoid arthritis synovial fibroblasts (RASFs) are active drivers of joint destruction in rheumatoid arthritis. …
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WebThese proinflammatory cytokines trigger the transformation of RASFs into an aggressive and invasive phenotype and are key players in the development of the well-known chronic, destructive inflammatory response in joints affected by RA. Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovitis, synovial hyperplasia and progressive … WebNov 26, 2024 · Less commonly, the hips, shoulders, elbows and neck are involved. It is often symmetrical. So, for example, if a joint is affected in a right arm, the same joint in … martavaleria.37
Rheumatoid arthritis - Symptoms and causes - Mayo Clinic
WebMar 1, 2024 · Rheumatoid arthritis (RA) and osteoarthritis (OA) are destructive joint diseases, the development of which are associated with the expansion of pathogenic T lymphocytes. Mesenchymal stem cells may be an attractive therapeutic option for patients with RA or OA due to the regenerative and immunomodulatory abilities of these cells. WebMar 9, 2024 · The inappropriate accumulation and activation of leukocytes is a shared pathological feature of immune-mediated inflammatory diseases (IMIDs), such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Cellular accumulation is therefore an attractive target for therapeutic intervention. However, attempts to modulate leukocyte … WebWhat is rheumatoid arthritis? Rheumatoid arthritis (RA) is a long-term (chronic) disease that causes inflammation of the joints. The inflammation can be so severe that it affects … data entrata in vigore gdpr